The Apothecary’s Notes Sequel PV Unveiled

The anime “The Apothecary Diaries” aired its final episode on July 4th, and after the broadcast, the production of a sequel was announced. In addition, a super teaser PV containing many hints for the “new story” that will be depicted in the sequel was released. The original author Hinata Natsu, main cast members Aoi Yuki and Takeo Otsuka have sent congratulatory comments.

The anime “The Apothecary Diaries” is based on Hinata Natsu’s light novel, which has sold over 40 million copies in total. It depicts the pharmacist Maomao (CV: Yuki), who has an abnormal obsession with poison and medicine, and the mysterious and beautiful eunuch Jinshi (CV: Otsuka), as they take on difficult cases that occur in the harem. The first season (24 episodes in total) was broadcast from 2023 to 2024, and the second season began broadcasting in January 2025.

The congratulatory comments from the original author, Natsu Hinata, and the cast are as follows:

[Natsu Hinata (original author)]

I’m very grateful that a sequel has been decided. On the other hand, the first and second seasons were originally intended to be the length of four novels. And the sequel… I’m under a lot of pressure to make it more interesting. I’ll double-check to see if there’s anything missing from the story and support the anime team. It’s still going on, so I hope you’ll all enjoy it.

[Aoi Yuki (voice of Nekoneko)]

I was so sad when the recording of the second season ended, so I’m so happy about the sequel! I’m also happy to be able to announce the sequel at this timing, which will surely erase the sadness of the end of this epic story. Everyone involved in every section of “The Apothecary Diaries” has a strong love for the work, and it is carefully prepared before being delivered to everyone’s homes, so we may have to keep you waiting a little longer for the sequel, but I’ve heard that there are plenty of measures in place to keep you enthusiastic and supportive in the meantime, so I hope you will continue to support us!

[Otsuka Takeo (role of Jinshi)]

Thank you to everyone who watched until the last episode of the second season. And it has been decided that a sequel will be produced! Congratulations! Thank you! I’m very happy that we will be able to continue watching and acting in the world of “The Apothecary Diaries” in the anime. There seems to be a lot of fun things happening until the sequel airs, so please continue to support us, including those!

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[Sequel production confirmed!] Super teaser PV for the anime “The Apothecary Diaries”

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A New Mystery Brews in the Shadows of the Imperial Court

The release of a super teaser PV for the sequel to The Apothecary’s Notes (Kusuriya no Hitorigoto) has ignited excitement among fans of the acclaimed historical mystery anime. With fleeting visuals and cryptic narration, the teaser hints at deeper conspiracies within the palace and further challenges awaiting Maomao, our sharp-witted apothecary. Given the series’ popularity and its intricately layered storytelling, this sequel may delve even more into political intrigue and Maomao’s mysterious past. The fact that a PV was released before an official air date suggests a major promotional campaign is underway, hinting at the studio’s confidence in the sequel’s success.